The symptoms of mesothelioma

This article contains the symptoms and signs of mesothelioma that may vary depending on where the cancer occurs: pleural mesothelioma, peritoneal mesothelioma and other forms of mesothelioma.


CT scan of a patient with mesothelioma, coronal section (the section follows the plane that divides the body in a front and a back half). The mesothelioma is indicated by yellow arrows, the central pleural effusion (fluid collection) is marked with a yellow star. Red numbers: (1) right lung, (2) spine, (3) left lung, (4) ribs, (5) descending part of the aorta, (6) spleen, (7) left kidney, (8) right kidney, (9) liver.


Signs and symptoms of mesothelioma vary depending on where the cancer occurs.

Pleural mesothelioma signs and symptoms may include:

  • Shortness of breath
  • Painful breathing (pleurisy)
  • Painful coughing
  • Chest pain under the rib cage
  • Unusual lumps of tissue under the skin on your chest
  • Unexplained weight loss
  • Dry (nonproductive) cough

Peritoneal mesothelioma signs and symptoms may include:

  • Abdominal pain
  • Abdominal swelling
  • A change in your bowel habits, such as more frequent diarrhea or constipation
  • Lumps of tissue in the abdomen
  • Unexplained weight loss

Other forms of mesothelioma
Signs and symptoms of pericardial mesothelioma and mesothelioma of the tunica vaginalis are unclear. These forms are so rare that not much information is available. Pericardial mesothelioma signs and symptoms may include difficulty breathing or chest pains. Mesothelioma of the tunica vaginalis may be first detected as a mass on a testicle.

When to see a doctor
See your doctor if you have signs and symptoms that may indicate mesothelioma. Signs and symptoms of mesothelioma aren't specific to this disease and, due to the rarity of mesothelioma, are more likely to be related to other conditions. If any persistent signs and symptoms seem unusual or bothersome to you, ask your doctor to evaluate them.


Content provided by Mayo Foundation for Medical Education and Research (MFMER)


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